(5alpha,6alpha,7alpha,12R,19alpha)-2,3-Didehydro-6,7-epoxyaspidospermidine-3-carboxylic acid methyl ester - Names and Identifiers
Name | Lochnericine
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Synonyms | Lochnericine (5α,12R,19α)-2,3-Didehydro-6α,7α-epoxyaspidospermidine-3-carboxylic acid methyl ester (5α,6α,7α,12R,19R)-2,3-Didehydro-6,7-epoxyaspidospermidine-3-carboxylic acid methyl ester Aspidospermidine-3-carboxylic acid, 2,3-didehydro-6,7-epoxy-, methyl ester, (5α,6α,7α,12R,19α)- (5alpha,6alpha,7alpha,12R,19alpha)-2,3-Didehydro-6,7-epoxyaspidospermidine-3-carboxylic acid methyl ester
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CAS | 72058-36-7
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(5alpha,6alpha,7alpha,12R,19alpha)-2,3-Didehydro-6,7-epoxyaspidospermidine-3-carboxylic acid methyl ester - Physico-chemical Properties
Molecular Formula | C21H24N2O3
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Molar Mass | 352.43 |
Melting Point | 190-3°C (dec.). |
Specific Rotation(α) | D27 -432° (chloroform) |
Appearance | Powder |
pKa | pKa in 66% DMF: 4.2(at 25℃) |
Storage Condition | 2-8℃ |
(5alpha,6alpha,7alpha,12R,19alpha)-2,3-Didehydro-6,7-epoxyaspidospermidine-3-carboxylic acid methyl ester - Introduction
Lochnericine is a natural compound, an alkaloid isolated from the soil of South Africa. Its chemical structure contains two pyrrole rings and two carbamoyl groups.
Lochnericine has antibacterial, antiviral and antitumor activities. It shows a strong inhibitory effect on a variety of bacteria, viruses and cancer cell lines, so it has potential value for drug development.
The method of preparing Lochnericine is mainly obtained by extracting South African soil samples in an appropriate solvent and separating and purifying them by column chromatography, solvent extraction and other methods. No industrial method of producing Lochnericine has been reported.
Regarding the safety information of Lochnericine, there are no detailed toxicological data or safety assessment reports for reference. Since Lochnericine is a natural product, more research is needed to evaluate its toxicity and safety. When using or studying Lochnericine, it is necessary to take appropriate protective measures and follow the laboratory's safe operating procedures.
Last Update:2024-04-09 21:54:55